SALLY
ANN LEDERMAN ANDPEDRO ROSSO
ABSTRACT
The effect of a 2-day fast on fetal and maternal
weight and composition was determined in adlibitum-fed and food-restricted
pregnant and nonpregnant rats. Fasting between days 17 and 19 of gestation
resulted in a greater loss of net maternal body weight in ad libitum-fed
pregnant than in nonpregnant rats and also a greater loss of body fat. In
contrast, food-restricted pregnant rats, also fasted from day 17 to day 19 of gestation,
maintained their net body weight and body fat during the fast as did nonpregnant
rats fasted for the same length of time. Fetal weight was not significantly
reduced by fasting in the ad libitum-fed rats but was reduced by 25% in the previously
food-restricted rats. The results demonstrate that prior maternal nutritional
status strongly influences the effects of fasting on the fetus and that
maternal nutrient stores are not mobilized for fetal utilization even when
fetal growth is markedly impaired. J. Nutr. Ill: 1823-1832, 1981.(deniaprianichan)
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